It was virtually the final touch of a magnificent campaign which saw City end the season with a record 16 away wins and 106 Premier League goals.
Manchester City trailed for a total of just 153 minutes in Premier League matches this season - the fewest by a side in a single campaign.
Saints looked to have secured the draw but, with virtually the final kick of the game, Jesus produced a flawless lobbed finish to spark wild City celebrations.
And now Sky Sports have captured Pep Guardiola side's dominance on English football this season with a brilliant info-graphic, highlighting all the records that the side have broken this season.
Washington Capitals vs. Tampa Bay Lightning, 5-13-2018 - Expert Prediction
Nashville and Winnipeg will decide the final third-round team Thursday in Game 7 of their Western Conference second-round series. Barry Trotz's Capitals took a 1-0 series lead Friday, as they scored the first four goals in a 4-2 victory at Amalie Arena.
Opposition striker Jesus broke free towards goal and lofted the ball over the stranded Alex McCarthy with the last kick of the game to send his team to 100 points, but ultimately the mood wasn't dampened after another passionate display from Hughes' men.
"I think [Virgil] van Dijk has helped them a lot to be more consistent in the defensive department, especially in the box, and (there is) the quality up front and the quality in the way they play".
The old record was held by Liverpool, who collected 98 points in the 1978-79 season (adjusted to three points for a win).
Manchester City star midfielder, Kevin De Bruyne, has won the maiden Cadbury playmaker of the season award.
"I need to give myself a shake because I'm a little bit flat because I felt we should have won this game against the champions", said Hughes, after City had beaten Saints with an injury-time goal for the second time this season.
The Buttler did it as Royals stay alive in IPL
For Rajasthan, Archer bagged couple of wickets but leaked 42 runs while Sodhi scalped one conceding 29 runs. All told, he took 31 runs off 14 balls from Kaul at a strike-rate of 221.42 and a control percentage of 85.
"Numbers are numbers, they are the outcome of the way we played".
But they had no intention of letting the impending party distract them on the south-coast. Dusan Tadic's corner was flicked goalwards by the head of Maya Yoshida, but Claudio Bravo produced a good save to keep it out.
Swansea City have been relegated after seven years in the Premier League.
Extending that form out over the course of 38 games is now the challenge for the German to deliver a first league title since 1990.
Mariners 2B Cano fractures hand on HBP
Tigers right fielder Niko Goodrum , playing for an injured Nicholas Castellanos , led off the fifth inning with a solo home run. Jose Iglesias hit a two-run homer for the Tigers, and Grayson Greiner contributed the first two RBIs of his big league career.