The BMC Racing Team was hoping for overall success in Tirreno-Adriatico but, even though that didn't work out for the American squad, it was still celebrating at the end of the race.
"I didn't want to lose Tirreno-Adriatico by a few seconds without trying to get the time bonus in the intermediate sprint", Kwiatkowski said.
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LottoNL-Jumbo's Jos van Emden was second on the stage, four seconds behind Dennis, with Team Sky's Jonathan Castroviejo a further four seconds back in third.
The Italian has quietly picked up top 10s in the Giro d'Italia and the Vuelta a España in the last four years, and also finished in 11th place at last year's Tour having ridden in support of Porte for the first half of the race.
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"I don't actually know the final result, just that I won, and that's all that matters", Kwiatkowski said. "I feel sorry for him, but we remained focused on our goal", Kittel said. Crucially, Caruso was only 37th, yielding another 21 seconds to his rival and thus missing out on GC victory.
The Pole found himself as Sky's leading contender when team-mate Geraint Thomas suffered a mechanical issue on Saturday's fourth stage. The overall victor said he was nervous because of the rain falling prior to his start, but felt well during the TT.
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Kittel, whose season got off to a slow start before winning stage two at Tirreno-Adriatico last week, latched onto the wheel of former team-mate Maximiliano Richeze before pulling out of his slipstream in the closing metres while denying a late charge from Peter Sagan. This is a attractive race with a lovely trophy. "I'm very proud of the team".