England's hardest fixture of the tournament is already shaping up to be their trip to France in the penultimate round but they are favourites to defend their title and are expected to beat a transitional Wales side, having won 63-0 in Cardiff previous year.
Warren Gatland knows what to expect from England.
REUTERSEngland and Wales players are involved in a scuffle during the Six Nations
"My gut feeling is JJ will start the game well against Wales".
'Eddie's told me to back myself, the first decision that comes into your head is probably the right one, ' Care said.
"When he tried to stop the referee from allowing the kick at goal - we can not have that in the game. To overtake him will be brilliant, but this weekend isn't about me, it's about England hopefully beating Wales". Another Frenchman, Jerome Garces, is in charge at Twickenham.
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Across the park, regional partnerships and combinations are being transferred onto the global stage and trusted to flourish in the Test arena, with Alun Wyn Jones providing the leadership from the engine room. "Garces won't let him intimidate him". "It's whether he has the bottle to handle it", Jones told a news conference. When it gets a bit cut and thrust, nip and tuck, this will be a proper Test match.
After every game we will always review our performance and see what lessons can be learnt, what we need to improve on, and looking to see if there was anything that we got very wrong in the game plan that we need to go away and practise.
"There's a lot of experience on either side, but who has Patchell going to look for?"
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"The magic now is to blend in players from other clubs, get them all playing the same style of rugby and it's great that they are playing the style that Scarlets are playing but obviously the national team should be stronger".
Davies' 9-10-12-13 combination with Scarlets teammates Rhys Patchell, Hadleigh Parkes and Scott Williams was as devastating on the Test scene against the Scots as it has been in club rugby and the scrum-half hopes that familiarity helps them on English soil. He hasn't played much Test rugby at all and he's their third-choice No10. Big games are made for big players.
The Six Nations is a fantastic tournament - having five fixtures in five weeks means that you get to keep having another go - against Italy we weren't great, but then five days later you get to go again against different opposition which is really nice and is why the Six Nations is such an important tournament. I think defensively they're going to be far sharper and quicker to put Wales under pressure.
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