Trump himself has lavished praise on Winfrey over the years, including in 2015, when he said that he would consider her as a running mate on his Republican ticket.
In a now-deleted tweet, NBC News also touched on the situation, posting a photo of Winfrey alongside the caption, "Nothing but respect for OUR president".
Nearly immediately talk of a possible presidential bid erupted on social media, while on Monday the airwaves and TV talk shows were alight with speculation about whether the most powerful African-American woman in the world could consider a presidential run.
"I slept on it and came to the conclusion that the Oprah thing isn't that insane", tweeted Dan Pfeiffer, a former senior advisor to Barack Obama, the president whom Winfrey was credited with helping to elect in 2008. Please enjoy this CNN article from August 1999 in which Warren Beatty was said to be "very seriously" considering a presidential campaign, running to the left of announced 2000 Democratic candidates Al Gore and Bill Bradley.
Her honor came in a year when the awards show, Hollywood's first leading up to the Oscars, was dominated by a scandal that has seen the downfall of dozens of powerful men as women break years of silence. "Now, some people are calling it the Golden Globes".
What she lacks is political experience.
Twitter won't block world leaders or delete their messages
Twitter responded in its blog post that even if it did block a world leader, doing so would not silence that leader. Trump critics claim the president's more bombastic tweets fall into that category.
And when asked if she could defeat over Donald Trump in the 2020 election, she responded, "I don't know".
Winfrey laughed while the studio audience applauded.
Gayle King, Winfrey's best friend, continued: "I thought that speech was incredible".
Oprah has made Weight Watchers an investor magnet since buying a 10 percent stake in the company over two years ago. But in another TV interview in October, she dampened speculation, stating, "There will be no running for office of any kind for me".
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They've won a lot of games this year by running the ball with Mark Ingram and Alvin Kamara . Still, there has been plenty of buzz in Minnesota about getting back at the Saints.
Winfrey's next role is in Ava DuVernay's movie "A Wrinkle in Time", which comes out in April. On Sunday night Winfrey's detractors immediately began circulating an old photo of Winfrey with Harvey Weinstein, the disgraced movie mogul who has become the symbol of Hollywood rot. Videos and transcripts of the speech were widely shared on social media on Monday morning. "I want her to run for president", Streep reportedly said after the show ended.
The Washington Post quoted Meryl Streep saying that Winfrey "launched a rocket" with the speech.
"I don't want to get political, but I think she could pull it off", said Chapman. "But now she doesn't have a choice".
Mayers referenced in his opening monologue comments he had made about current USA president Donald Trump during the 2011 White House Correspondents' Association Dinner. You do not have what it takes!' Meyers said on Sunday.
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Police told WDIV News in Detroit that the home where the girl was found was full of animal waste and contained guns and drugs. Fields, the mother's boyfriend, has been charged as a habitual offender, Sumpter Township police wrote on Facebook.
The laughs and cheers from the crowd made it clear: Winfrey would have a lot of supporters in the entertainment industry.