A fresh Saudi-led airstrike hit a residential neighborhood overnight in central Yemen's capital Sanaa, injuring at least six residents and completely destroying four resident houses, a Xinhua photographer at the scene said on Saturday.
Two air strikes targeted the ministry late on Friday and plumes of smoke could be seen billowing from the building, the rebel media network Al Masirah quoted witnesses as saying.
'Everyone was afraid. Minutes later, another strike hit my neighbour's house. The casualty toll could rise as rescuers search through the rubble for survivors.
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A number of houses were also reportedly damaged in the strike.
The United Nations, along with dozens of other aid groups, are raising alarm at the blockade imposed on Yemen by the the US -backed, Saudi-led coalition there, saying Thursday it could lead to "the largest starvation the world has seen for many decades". While Tehran has firmly denied its involvement, Saudi Arabia still holds Iran responsible for the attack. "It will be the largest starvation the world has seen for many decades, with millions of victims".
The blockade has already impacted millions, with malnutrition now common across the country, particularly in the north, and upwards of a million people coming down with cholera in the worst outbreak in human history, which killed over 2,000 people alone.
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Saudi Arabia and its allies intervened in neighbouring Yemen in March 2015 with the stated aim of rolling back Huthi rebel gains and restoring the government of President Abedrabbo Mansour Hadi to power.
The conflict has left more than 8,650 people dead, including many civilians.
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Although full emergency procedures were deployed, the airport remains open, an airport spokeswoman said. There were 53 passengers including a baby and four crew members on board.