The England star suffered a groin strain in Sunday's 0-0 draw at Chelsea.
Despite potentially losing Welbeck, who missed eight months of 2016 with a knee cartilage problem, once again, Aaron Ramsey believes Arsenal have proved they can compete with the top teams in the Premier League. Welbeck underwent preliminary scans on Monday and will be assessed further today.
"Danny has a scan today, we don't know how bad his groin injury is but he will certainly be out until the worldwide break", Wenger told Arsenal's official website on Tuesday ahead of Wednesday's Carabao Cup fixture against League One side Doncaster Rovers, coached by Sir Alex Ferguson's son Darren.
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But he is nearly certainly out of England's final two World Cup qualifiers against Slovenia and Lithuania early next month. Arsene Wenger is clearly a fan of the forward, and has nearly always found a place for him in the starting XI when he's been fit.
And Welbeck has repaid his manager's faith, scoring three goals - making him the Gunners' leading goalscorer this season.
But since joining the north London club in 2014-15, the 26-year-old has appeared in over 20 league games only once.
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The English worldwide is also likely to miss World Cup qualifiers against Slovenia and Lithuania.
Welbeck's return to the worldwide fold after a long term injury absence arrived as a huge boost to Southgate, who has identified the former Manchester United star as a key member of his squad.
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With the Rohit Sharma- Eden Gardens love affair is well known, it won't be a surprise if he scores big in the match on Thursday. Not panicking as such. "I love every format of the game", he added. "We're making silly errors when we're under pressure".